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Ecosecurities (2002) estimates the costs of validation at between $18,900 and $37800 and verification costs at about $9400 per audit.
13 The estimated cost of the method (excluding the costs of validation) was 1,995 Malawian Kwacha (MWK) or 7 US dollars (USDs) per completed mobile phone interview (exchange rate for October 1 , 2012.
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Because of this the cost of validation is prohibitive.
But to realize those opportunities, society itself must be willing to bear the costs of biomarker validation and the ethical challenges that come with exposing individuals' vulnerabilities to disease.
Considering the investment cost of target validation, one needs to rank genome-sized output data in favour of proteins that can readily be modelled using homology modelling, as these structural models can be used in virtual high throughput screening (vHTS) of large compound libraries [1] [3].
However, the cost of such validation demands a high degree of confidence in the knowledge extracted from microarray data by marker identification and clustering algorithms.
These have the upside of providing biologically validated results, but they also have the downside of not being comprehensive due to the limited number of spots on genotyping arrays and the prohibitive cost of Sanger validation when performed thousands of times.
However, they also pointed out that these costs also depend on the expertise of the project developers, because low quality project design documents significantly increase the costs of third-party validation and verification.
Computational costs and validation of models creates a need for cost effective decision making with regards to experiment design.
In this paper, an optimization-based formulation is proposed by coupling the costs of product design and validation testing, in order to ensure the product reliability with the minimum number of tests.
The main challenges are the scale of the problem and the costs of the necessary experimental validation (Evanko, 2009).
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CEO of Professional Science Editing for Scientists @ prosciediting.com