The pull factors are cost-effective trials, with data transfer to developed countries being legitimized by the World Trade Organization ( WTO), patient numbers, disease profile, and availability of highly adaptable internationally trained investigators who have no language barriers.
The process of screening and recruitment of participants to trials can then be significantly speeded up reducing the risk and cost to pharmaceutical companies, thereby leading to more efficient and cost-effective trials.
Because of the low incidence and prevalence of patients with FSGS, an efficient and productive study design that fosters collaboration is essential to implement cost-effective trials and to identify and recruit clinical subjects in a timely manner.
Cost-effective clinical trials targeting genes, not tissues, and enrolling patients with different types of cancer could be supported by these organizations to accelerate the discovery of new cancer cures.
This strategy is essential if efficient and cost-effective clinical trials are to be conducted in the preclinical stage of Huntington's disease.
Thus, insights gleaned from "gene to function" studies could be translated into designing more efficient and cost-effective clinical trials for immune-targeted drug therapy in chronic inflammatory diseases.
Quantitative and molecular nuclear medicine imaging should be an integral part of the design of intelligent, cost-effective clinical trials at the cutting edge of research.
More effective new drug candidates, perhaps combined with biomarkers (e.g., genetic testing) to identify the subset of patients most likely to benefit, could demonstrate efficacy in smaller, more cost-effective clinical trials.
21 Where the sensitivity analysis assumed the use of the cheapest metal-on-polyethylene implants (without incorporating a possible impact on quality of life), RSA was no longer cost-effective within-trial.
If telehealth and telecare technology proves cost-effective in our trial, it will provide additional options for health services worldwide to deliver care for populations with high levels of need.
