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Using choice modeling, we found that all participants who completed the survey selected sensitivity as their top priority issue for a building a new STI POCT, followed by cost, specificity, and time.
The six attributes ranked from high to low as follows: cost, specificity, process, sensitivity, preparation and pain.
From most important to least important, they ranked as follows: cost, specificity, process, sensitivity, preparation and pain.
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However, this threshold could be lowered at the cost of specificity, and will naturally vary depending on the specifics of the sample processing steps used such as enzyme fidelity and number of PCR cycles.
In the specific case of EBOV, conjugation to cholesterol enhanced potency but at the cost of specificity.
While it may improve sensitivity for sacroiliitis this may be at the cost of specificity.
These markers are valuable markers with the characters of low cost, high specificity and stability.
The RF models have a bias towards sensitivity at the cost of specificity, whereas this bias is not so pronounced in the SVM models.
For example, at application of one-class SVM [30], we have got 100%% sensitivity; however, on the cost of specificity, it has dropped to 79.4%%.
The experience in Russia, where lay interviewers were employed [13], suggests this is possible to some degree but at a cost in specificity.
Rapidity, low cost, high specificity, good sensitivity, and portability of the device are unique advantages related to LFA strips [85, 86].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com