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Using a lower cost regimen for first-line treatment can potentially reduce the overall cost of chemotherapy.
Clearly the costs per life year gained are very high and many healthcare systems will have difficulty in accepting this high cost regimen as standard (Norum et al. 2005).
A discrete choice experiment conducted through a web-enabled online survey was used to estimate the relative importance of eight medication factors (immediate and long-term medication harms and benefits, cost, regimen, symptom severity, alcohol restrictions) on the preference to continue taking a medication.
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Using lower cost regimens such as IRIS as first-line chemotherapy can lead to a reduction in overall costs for the entire course of chemotherapy, because the duration of first-line treatment was longer than the duration of second and subsequent lines of chemotherapy.
14 A series of univariate analyses were carried out on some parameters of the simulation model, such as virological response, HAART-cost regimen, and probability of adverse events.
This platinum-based chemotherapy is an effective, well-tolerated and low-cost regimen for patients with MBC, including those pretreated with anthracyclines.
However, nab-paclitaxel had the most favorable safety profile, which translated into lower costs for side-effects management (Table 4) When the cost of treating side effects was added to the overall cost per course, nab-paclitaxel remained the highest-cost regimen.
These factors include medication costs, regimen complexity, the patient's emotional well-being, and the patient's perceptions of medication side effects and medication-related intrusions on activities of daily living.
Compared with no routine prophylactic ART, programme 1D is the most cost-effective regimen costing 556 USD to avert one paediatric HIV infection.
Specifically, those factors were those concerning the harms or benefits of the medication as well as cost and regimen.
Six of the eight factors (i.e. immediate and long-term medication harms and benefits, cost, and regimen) had a significant influence on medication choice.
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