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The latest guidelines used the Grading of Recommendations, Assessment, Development, and Evaluation methodology [ 2], which assigns a measure of the strength of the recommendation based not only on the evidence, but also on factors such as cost, plausibility, toxicity, and clinician acceptance.
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Following this example, the Academics took their premises from the doctrines of their Stoic opponents or from assumptions that the Stoics could not reject or could reject only at a high cost in plausibility.
These studies did not, however, pursue the nature and costs of replacements to insect pollination, and no other such studies have attempted to calculate the plausibility and cost of substituting insect in the pollination of crops.
The control for tight band-width in cost modules and further plausibility checks can lead to the exclusion of cases from the calculation, even if costs are calculated correctly.
OMB estimates that the corresponding benefits of these regulations amply outweigh the costs, but the sheer magnitude of the costs at least reinforces the plausibility of the theoretical expectation that regulation discernibly affects employment.
3 In order to cross-check the plausibility of our direct cost estimates, we compared our results with national health-care cost statistics for the year 2005 [ 8].
Validation and plausibility checks revealed that cost data were about 80% complete.
This project evaluated the plausibility of recently developed cost measures.
We define 'most promising treatments' as those that (i) appear to have clinically important effects that are maintained in the long term, (ii) are readily available and of modest cost and (iii) there is biological plausibility for the effect.
Furthermore, a break-even analysis is included among the sensitivity analyses, to enable judgement of the plausibility that the intervention is cost-effective, showing that such a small number as 9 avoided hip fractures is sufficient to reach a cost-effective result.
Although this approach adds to biological plausibility to our study and is more cost-effective than the epigenome-wide approach, we did not conduct a systematic screening of all genes that are potentially affected by phthalate exposure.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com