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Research of this kind will also assist in the identification of patients in need of the most intensive interventions while providing easily accessible data for establishing the cost of sustained intervention (e.g., [ 41]).
Since granule cells represent the most abundant neuronal type in the brain, and spikes are energetically expensive (Attwell and Laughlin, 2001; Carter and Bean, 2009), the metabolic cost of sustained firing in this population would be considerable (Howarth et al., 2012).
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The total bill would still be a lot smaller than the cost of sustaining a huge American fighting force there.
As to the high cost of sustaining a large Afghan military after 2014, she added, "We fully recognize this reality.
"Continued high attrition increases the overall cost of sustaining the force and creates a burden on recruiting and training structures".
As part of its due diligence, the museum has hired Bain & Company to assess the cost of sustaining the expansion long-term.
The government said last spring that it could no longer afford the estimated $200 million annual cost of sustaining Mir, and planned to bring it down unless private money could be found.
Duncan said people might find that the cost of sustaining their lifestyle in some developments -- including high transportation costs to far-away jobs -- is greater than the cost of the home.
Each are reportedly suffering from cash issues, however, due largely to the high cost of sustaining their fierce rivalry with one another, as well as dozens of other bike-sharing startups that emerged over the past few years.
The total programme cost is now estimated at about $400 billion, while the cost of sustaining the aircraft over their expected 30 year life is expected to run over $1 trillion, a figure that has led to headlined dubbing it – whether fairly or not – the "trillion dollar fighter".
The rising cost of sustaining a growing class of elderly is consuming an ever greater share of our national wealth.
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