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Here, we show that receptor uptake is well described by a thermodynamic trade-off between receptor-vesicle binding energy and the entropic cost of confining receptors within endocytic vesicles.
According to a report by the Youth Advocate Programs, these programs can successfully serve three to four youth in the community for the cost of confining one youth in an institution.
The additional cost of confining an inmate to death row, as compared to the maximum security prisons where those sentenced to life without possibility of parole ordinarily serve their sentences, is $90,000 per year per inmate.
To replicate the ionic strength dependence of the COC, we developed a quantitative model of the electrostatic energy cost of confining charged monomers within the volume of an amyloid oligomer.
To compute the electrostatic free energy cost of confining monomers to the volume of an oligomer, we treat the monomers and oligomers as spheres of radius 1.6 nm and 3.8 nm, with isotropic surface charges of 15 e and 120 e, respectively.
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A similar report ("CAFOs Uncovered: The Untold Costs of Confined Animal Feeding Operations") by the Union of Concerned Scientists (UCS) was also released in April, reaching similar conclusions and making similar recommendations.
Finally, the entropic cost to confine the molecule in the pore is minimal.
The technical constraints introduced by diesel-generators along with the high cost of storage options confine the penetration of renewable energy sources (RES) in these systems.
Most people think the cost of investing is confined to the costs of operation, the management fees and trading costs.
It would seem that such small sums can't change business fortunes, especially because cost of buybacks is confined to the balance sheet and doesn't make it to the income statement.
Ratio of the volume of transverse confining steel to the volume of confined concrete core.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com