These results were then used to design optimal combined bisulfite restriction analysis, SIRPH, and pyrosequencing assays for accurate and cost-efficient assessment of MGMT promoter methylation.
Urinary mutagenicity has been examined in occupational and environmental settings for more than three decades as a general cost-efficient assessment of systemic genotoxicity (Cerná and Pastorková 2002).
The DNA-damage-reporting biosensor presented here offers new possibilities for user-friendly and cost-efficient assessment of DNA damage in a variety of nano- and microsystems.
The methodology presented herein not only allows for a prolonged monitoring of metabolic changes subsequent to transfection till the achievement of maximum protein activity, it also facilitates the time- and cost-efficient assessment of SNPs and other mutation/deletion associated protein modifications that may affect protein activity, stability or its intracellular localisation.
This type of gait assessment is cost efficient, quick, and easy to use in comparison to computer-assisted gait analysis [ 1, 3, 4].
One of the overarching goals of our research on cost-efficient exposure assessment is to investigate the costs of exposure assessment in field-based studies of musculoskeletal risk factors.
A time and cost efficient approach to functional and structural assessment of living neuronal tissue.
Then, the general model is simplified, and procedures are derived for identifying optimally cost-efficient exposure assessment strategies, depending on the shapes of cost functions.
A recent review attempted to summarize the state of inquiry into cost-efficient exposure assessment of occupational exposures and identified only nine articles systematically addressing this area [ 11, 12].
Obviously, both for regression metrics, exceedance, and ICCs, optimally cost-efficient exposure assessment strategies may deviate from those driven by the objective of obtaining precise exposure means, as illustrated by two studies on optimal measurement allocation in reliability studies [ 69, 70].
