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Potential uses include point-of-care diagnostics and lab-on-a-chip applications for global health, where the quantitation of labelled and unlabelled proteins on the same device may be necessary and cost efficacy is highly relevant.
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Clinical efficacy and cost-efficacy are thus important in allocating limited resources for treatments.
76 Available evidence for cost-efficacy was at a high risk of bias 81 82 or outdated.
The cost-efficacy was assessed by calculating the incremental cost-effectiveness ratio (ICER) per subject achieving PASI 75 and PGA 0/1.
These measures of cost-efficacy are less impressive when considering an NNT of 1 to prevent a death with cost-saving therapy for critically ill patients with AIDS not on antiretroviral drugs [ 26].
Shorter treatment durations would further reduce estimated costs if efficacy is shown.
Unfortunately, Obamacare's mission to reduce costs and improve efficacy is targeted more at comparative effectiveness research - i.e., the attempt to reduce costs by looking at the most effective strategic and clinical treatments based on statistics-based methodologies.
Production of a recombinant FIX (rFIX) with enhanced clotting activity, offering the possibility of fewer infusions and fewer costs with similar efficacy, is one of the current challenges for hemophilia B treatment.
Bioremediation is a low-cost technology, whose efficacy is often enhanced with preliminary mild physical chemical remediation methods.
Despite its long-time requirement, bioremediation is an alternative low-cost technology, whose efficacy is often enhanced with preliminary mild physical chemical remediation methods [4, 5].
Vaccinating children from 1 to 4 years of age in the high-risk districts costs < $500 per DALY averted and is very cost-effective when vaccine efficacy is 65%.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com