Threshold analyses of the modelled strategies are employed to assess the strategies potential for cost-effectiveness, running scenarios with health outcome improvements ranging from 1% to 100%.
It turns out that the only thing keeping the human gaming community in with a chance is the sheer difficulty, tedium, and cost-effectiveness of running the bots at a profit.
The cost-effectiveness and running costs are currently being evaluated by combining vaccination coverage and cost data of both sectors and including household costs.
Additionally, we examined the impact of HPV 6 and 11 protection in HPV4 on cost-effectiveness by running a scenario without the HPV 6 and 11 protection.
To investigate the impact of COPD severity on the cost effectiveness of the bronchodilators we ran sensitivity analyses with the base-case scenario, assuming that, at the start of the model, 100% of the patients had either moderate, severe or very severe COPD.
As per the SPC for OLAI [ 14] a sensitivity analysis was also run examining the cost effectiveness of a 210 mg/2 weeks starting dosing (keeping the maintenance dose equivalent to 300 mg/4 weeks) schedule and was found to have a negligible impact on the results (see Table 8).
In 94.7% of those runs, the cost effectiveness ratio for vaccination fell below per capita gross domestic product, our conservative criterion for cost effectiveness.
Just one study to date has used Markov modelling to estimate the cost effectiveness of policies over the long run [ 65].
17 The analyses were run to evaluate global costs, cost effectiveness ratios (costs per case of Down's syndrome diagnosed), and incremental cost effectiveness ratios comparing all 19 screening options.
Proton has a medium-throughput, cost effectiveness and rapid turnaround time (just 4 h of sequencing run time).
Both were run in the model and the result in terms of cost effectiveness was markedly in favour of diathermy, despite its current unpopularity.
