Annualisation of costs and effects enables us to model cost-effectiveness over time horizons different to the observed trial period.
Therefore, these 4 rescue strategies were included to compare their cost and effectiveness over time.
There were significant correlations between average levels of individual costs and effectiveness over time (posterior expectation E [ ρ 1, 3 | data ] = 0. 32 and CrI (0.00,0.57)), and the individual slope of effectiveness ( E [ ρ 1, 2 | data ] = - 0. 17 CrI (-0.33, -0.00)), which cannot be explained by the background information included in the regression models.
For the first time prospectively collected controlled-trial data on survival, costs and cost-effectiveness over a time horizon of three years are presented.
The relative magnitudes of incremental costs and benefits determine imatinib's cost-effectiveness over longer time horizons.
7 8 Combining data from various sources to estimate cost-effectiveness over extended time horizons, modelling studies inevitably require a large number of assumptions, 26 and comparisons to our trial-based results are hampered by the great methodological differences.
Further, this analysis has captured costs and benefits during the program cycle; future analyses could measure or model costs and benefits over a longer timeframe to estimate some of the potential longer-term impacts of this program strategy, and whether effectiveness and cost-effectiveness might increase over time.
Fig. 2 Cost-effectiveness results over time horizons of 3 7 years.
We compared the 2 strategies in terms of incremental cost-effectiveness ratios over time horizons of up to 10 years.
We hope that developments in new technology and future innovation will improve the cost effectiveness of these measures over time and that this can drive consumption down further to an average of 120 l/p/d per day by 2030.
Unfortunately, neither review identified costs per QALY gained, decreasing its comparability with studies on other health behaviours, nor did they include cost-effectiveness over a longer time horizon.
