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Making the technology cost effective will be another challenge for Cogenra.
Whichever is most cost effective will be the hub of the decision". "I've played in some very big cup finals - and blessed to win a couple there - and it's good, but I believe it misses something.
The cases where laparoscopic surgery may be considered cost effective will be pre-defined and the mean differential costs and QALYs will be calculated in order to assess whether any of these conditions are satisfied.
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46 The uncertainty surrounding the decision to accept a treatment as the most cost-effective will be explored in cost-effectiveness acceptability curves (CEAC).
The probability that the group CB programme is cost-effective will be depicted using a cost-effectiveness acceptability curve, and one-way sensitivity analyses used to judge potential impact of other sources of uncertainty.
As the underlying willingness to pay is unknown, the probability of the intervention being cost-effective will be presented as a function of a varying willingness to pay in cost-effectiveness acceptability curves.
That's not bad for a proof-of-concept demonstration, but making it more efficient and thus cost-effective will be essential.
Whether additional interbody fusion or disc prothesis is necessary and cost-effective will be determined by this trial.
Whether Percutaneous Laser Disc Decompression has at least as much efficacy as the standard surgical procedure, and is more cost-effective, will be determined by this trial.
This is because as the disease burden at baseline increases with the increasing number of deaths, the benefit of the vaccine in reducing the disease burden will also be higher in absolute value, the slope of the line in Fig. 4 will be lower and therefore the price range over which the vaccine is cost-effective will be larger.
The overall significance here is that future PBAC decisions not to list 'innovative' new drugs from US companies (because they were judged not cost-effective) will be made in the shadow of possible US trade retaliation in important areas such as manufacturing and agriculture[ 34].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com