Option 2B is the least cost-effective regimen at more than three times the cost per additional case prevented.
Compared with no routine prophylactic ART, programme 1D is the most cost-effective regimen costing 556 USD to avert one paediatric HIV infection.
Based on our findings, antihypertensive therapy that is diuretic-based and that includes either low-dose reserpine or atenolol represents a cost-effective regimen in preventing or delaying cardiovascular events in older adults.
Measures which are being used range from sending laboratory test results by email, home delivery of the drugs to the patient, which is exempted from VAT in the UK, to using the most cost-effective regimens [13].
However, starting PLHIV on cost-effective regimens earlier, will maintain them in better health, resulting in the use of fewer health or social services and thereby generating fewer treatment and care costs, while enabling them to remain socially and economically active members of society.
Cost-effective regimens are also advantageous.
Several economic evaluations of regimens including oral preparations such as capecitabine and tegafur-uracil have shown that such regimens are more cost effective than regimens comprising only injectable preparations [ 15, 30– 30].
During the intervention period AS & AQ monthly was the most cost effective IPTc drug regimen at US$67.77 (61.71 74.75, CI 95%) per malaria case averted based on intervention costs only, US$64.93 (58.92 71.92, CI 95%) per malaria case averted once the provider cost savings are included and US$61.00 54.988, 67.99, CI 95%) when direct household cost savings are also taken into account.
When compared with other regimens, BEV-containing regimen was reported to be cost effective in two cost-effectiveness studies (incremental cost-effectiveness ratio [ICER] in the range of US$30,318 US$54,317 per life year) but not cost effective in the other three studies (ICER over US$300,000 per life year).
In a US study long-term treatment with biphasic aspart Mix 30 in insulin-naïve type 2 diabetic patients as part of a triple-therapy regimen was more cost effective than insulin glargine, with an incremental cost-effectiveness ratio of $US46 533 per QALY.
