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The cost-effective plane provided the judgment that annual G-FOBT and colonoscopy every 10 years were dominated by I-FOBT screening, irrespective of annual or biennial repeated period.
When we analysed the cost effectiveness outcomes by parity, all bootstrapped incremental cost effectiveness ratios for planned birth at home in nulliparous low risk women without complicating conditions fell in the south west quadrant of the cost effectiveness plane (less costly, less effective) (fig 2).
Cost effectiveness planes and acceptability curves showed that integrated care was cost effective compared with usual care for return to work and QALYs gained.
Using this method for assessing cost-effectiveness, strategies on the frontier (bottom right) of the cost-effectiveness plane are considered to be cost-effective.
Cost-effectiveness scatter plots showed that CIs of ICER located in the southeast quadrant (more effective and less costly) on the cost-effectiveness plane.
These were plotted on a cost-effectiveness plane to illustrate the probability of being cost-effective for both countries' willingness-to-pay (WTP) thresholds (figure 3).
The bootstrapped cost-effect pairs were plotted on a cost-effectiveness plane (CE plane) [ 20].
The results of the MCS are provided as an incremental cost-effectiveness plane, with ICERs <£0 and £20 000/QALY gained considered economically dominant and cost-effective, respectively.
24 The curves display the proportion of bootstrapped ICER-pairs that are cost-effective, meaning that they either fall within the south-east quadrant of the cost-effectiveness plane or remain below the λ threshold in the north-east and south-west quadrants of the plane.
The four quadrants of the cost-effectiveness plane are as follows: northeast, compliance with CPGs more costly and more effective than non compliance; southeast, compliance less costly, more effective; northwest (more costly, less effective) and southwest (less costly, less effective).
If the intervention were 100% effective in reducing preventable adverse events, it would 'dominate' (table 6 it would be both effective and cost-saving, placing it in the southeast quadrant of the cost-effectiveness plane.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com