Pharmacoeconomic environment in the field of osteoporosis offers new opportunity to optimize patients' management on the condition that cost-effective adherence-enhancing interventions be identified and carried out.
Although colorectal cancer (CRC) screening reduces CRC mortality and appears to be cost effective, CRC screening adherence is suboptimal.
The study will determine whether additional glaucoma education using BCC is beneficial and cost effective in improving adherence with glaucoma therapy.
Several investigators have developed and evaluated cost effective programs and adherence to hospital antibiotic guidelines to control antibiotic abuse [ 15- 17].
The evidence-based knowledge gained with this research will provide an understanding of the best (clinically effective, high adherence, cost effective) exercise program for this population and will help strengthen research in this field.
In addition, in settings with low adherence, it might be more cost effective to implement low cost adherence interventions such as counselling and pill counts before viral load testing.
Nevertheless, the key conclusion of this study is that PrEP can be a cost effective intervention given high efficacy, good adherence and long-term use, especially if sexual disinhibition is prevented.
These analyses show that in spite of higher initial development costs than for clinician-delivered interventions, a computer-delivered intervention may be a cost effective strategy for improving medication adherence in persons treated for HIV.
Our conclusions are also consistent with those of Goldie et al. [ 52] who argued that even adherence interventions with modest effects may be cost effective, and Freedberg et al. [ 53] who showed that a nurse-led adherence intervention was cost-effective with a cost per QALY of $14,100 compared to usual care.
44 45 This suggests that the reduction of fracture risk associated with high adherence might be larger, and enhanced adherence should become more cost effective, than that quantified by our study.
We note that for any intervention to be "cost effective" as a means to enhance adherence to medicines, it would have to be effective in reducing the burden of illness associated with non-adherence at an optimal level of resource use.
