Mr. Obama has been losing support among independents and is struggling to convince voters that the benefits of his signature legislative achievements -- the health care overhaul and the economic stimulus bill -- will outweigh the costs and drawbacks.
Recall biases, small sample sizes and costs are drawbacks to longitudinal studies.
Make sure that every card is balanced — that the more powerful cards impose some kind of cost or drawback.
Although a range of commercial surfactants is used as emulsifiers, their toxicity and high cost are significant drawbacks.
Although there are software tools capable of paneling complex geometries, their complexity and cost are serious drawbacks when architects consider using them.
CT has a high accuracy but severe drawbacks: cost (a real problem for most patients on Earth), transportation of critically ill patients, delay between CT and the resulting therapy, renal issues, anaphylactic shock, mainly high irradiation [64, 65].
Even though generally well-tolerated, such treatments have some drawbacks: cost, need for continuous treatment, increased risk of cardiac toxicity and, mainly, frequent onset of resistance to therapy.
Furthermore, need for numerous retreatments with possible adverse effects on physiological choroid [ 4- 7] and concerns about cost are important drawbacks of monotherapy with PDT.
However, the POC CD4 approach has drawbacks: cost per CD4 count test is higher, quality assurance in testing is more difficult to ensure, and already stretched human resource, logistics, and supply chain management of PHCs would be further burdened.
CT has a high accuracy but severe drawbacks: cost (a real problem for most patients on Earth), transportation of critically ill patients, delay between CT and the resulting therapy, renal issues, anaphylactic shock, mainly high irradiation [ 64, 65].
