Sentence examples for cosmic genes from inspiring English sources
The shorter average path length for COSMIC genes towards known cancer genes compared with OMIM and non-cancer genes may indicate that COSMIC genes are more likely to be involved in cancer related cellular pathways.
Interestingly, COSMIC genes with somatic mutations in cancer samples have higher scores than other genes in the COSMIC database.
Cancer and COSMIC genes show higher clustering coefficient than OMIM and non-cancer genes.
The similarity between COSMIC genes with cancer genes indicates that many COSMIC genes are likely to be putative cancer genes and should be distinguished from the non-cancer gene set.
COSMIC genes showed relatively more similarities with cancer genes in many properties, and in fact many COSMIC genes were found to be involved in cancer although they are not included in the Cancer Gene Census database [ 15].
COSMIC genes and OMIM genes in turn have distinctive features between each other and from non-cancer genes.
Another two (MYB and MLH1) are grouped into CL3 and the remaining one (hCAD) is not among the COSMIC gene list.
> -wrap-foot> KyotoKyoto Encyclopedia of Genes and Genomes Database, NES Normalized Enrichment Score Using published COSMIC gene expression profiles of 57 SCC cell lines with half maximal inhibitory concentrations (IC50 values) for various anticancer drugs, ssGSEA analysis was performed.
Query #3: 'Find variation information in Ensembl for all genes from mutated samples with a primary site of breast, and display COSMIC gene, mutation and sample information along with Ensembl variation information' (Table 4).
When comparing the congenital ALL samples with 28 control exomes from children without cancer sequenced in the same laboratory and analyzed with the same workflow, there were no statistically significant differences between mean numbers of mutations that overlapped with Cosmic germline genes or DNA repair genes (Table 3).
Since the comparison is based on a tumor sample, which may contains genomic aberrations that could differentially affect the performance of each technology, we investigated the coverage differences in COSMIC cancer genes.
