Ancient Egyptians were among the first to use minerals such as sulfur as cosmetic substances.
Other potentially interesting fields of study could include the analysis of different dilutions of BoNT/A and comparisons between different products, including between different pharmaceutical or cosmetic substances claiming to reduce the activity of mimetic muscles in the face or neck area.
BOTOX -- Though a cosmetic treatment, this substance can minimize some effects of photoaging.
COLLAGEN -- Also a cosmetic treatment, this substance, which is derived from the skin of cows, acts as a filler for lines and wrinkles.
A further 150 chemicals require exposure risk mitigation measures which means that they may only be used under certain conditions (e.g., formaldehyde or methanol in Annex III of the Cosmetics Regulation: list of substances which cosmetic products must not contain except subject to restrictions laid down; [1]).
Only a few years later, Gersuny became the first to use the injection technique for cosmetic correction; the injected substance was paraffin.
The substances may be potential cosmetic ingredients or potential PBT substances.
It must be questioned whether the ingredient lists are sufficient information for safe handling (b) Examples where natural substances and cosmetic products are granted special waivers Cosmetic products are not classified and labelled, even if they contain dangerous substances above the thresholds ([8] (A) Art. 1 (5)) Consumers have the right to know.
For all ages nationwide, the substances most commonly involved in human exposures are analgesics – common painkillers – followed by cleaning substances and cosmetic products.
In comparison, the smartphone application ToxFox by Friends of the Earth Germany [8], which had been launched in 2012, offers information about endocrine substances in cosmetic products.
