Sentence examples for cortex of the proband from inspiring English sources

Insoluble tau was extracted with sarkosyl from the frontal cortex of the proband, as described [ 9].

Sarkosyl-insoluble tau extraction from the frontal cortex of the proband with the K298E MAPT mutation confirmed that 4R tau was the major component, although some 3R tau was also present (Fig.  5b).

Score '++++' corresponded to >20 lesions For quantitative RT-PCR analysis for the three known C9orf72 transcripts [ 9], we extracted RNA from the frontal cortex of the proband, three heterozygous C9orf72 FTD cases and four pathologically confirmed controls without neurodegenerative disease.

Soluble tau was extracted with perchloric acid as described [ 8] from the frontal cortex of the proband, from the frontal cortex of a patient with the I10+3 G>A intronic MAPT mutation [ 26] and from the frontal cortex of a control subject.

To measure the level of expression of tau isoforms, soluble tau was extracted with perchloric acid from the frontal cortex of a patient with the I10+3 mutation, normal adult human brain and the frontal cortex of the proband with the K298E mutation.

Ancestors of the proband were surviving cohorts and it is possible that genetic selection through differential survival/fertility might explain the findings.

The paternal grandfather's age when the father of the proband was born was not coherent with the exposure during his SGP.

If food was not readily available during the father's slow growth period, then cardiovascular disease mortality of the proband was low.

All surveys except the one by Stewart et al. found that first-degree relatives of probands had a significantly increased risk of the proband's disorder as compared to the general population [7 15].

Compared to the general population, first-degree relatives of probands with migraine without aura, migraine with aura, chronic tension-type headache and cluster headache has a significantly increased risk of the proband's disorder.

Genomic DNA was extracted (DNeasy; Invitrogen) from the probands' skin fibroblasts and from a blood sample of the proband and her unaffected mother.