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However, these results need to be corroborated in a large sample that includes measures of biochemical iron status.
Although these findings were corroborated in a large single-center cohort study [ 5], they were not confirmed by subsequent randomized trials [ 6- 10].
Although some clinical studies confirmed that plasma presepsin levels were significantly increased in septic patients, and were positively correlated with the severity of sepsis, the sample sizes were relatively small [ 4- 9], and these findings have not yet been corroborated in a large number of septic patients in the ED.
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Our findings should be corroborated in a larger randomized, controlled clinical trial.
The risk of NAC involvement has been corroborated in a larger retrospective series of 286 SSMs, 16 (5.6%) were found to contain tumour in the NAC [ 27].
However, this study was limited by the small number of subjects completing the RCT (n = 23), and these results need to be corroborated in a larger RCT.
To confirm if this important finding could be corroborated in a larger data set, we then analyzed combined data (from the current study and previous data) with an additional 122 records, for a total of 77 OSCC cases and 145 controls (Table 3).
Due to the restricted number of bi CEBPA-mutated patients with high BAALC expression in our cohort it has to be corroborated in a larger cohort, whether bi CEBPA patients with high BAALC expression levels define a separate prognostic group within the CN-AML.
Clearly, the findings of this study need to be corroborated in a future large study; however, the concept introduces a simple and patient friendly luteal phase support, avoiding vaginal applications, discharge, and painful progesterone injections [ 36].
Kostek et al. [15] recently found an association between the MSTN 153R allele and maximal isometric contraction of the elbow muscle flexors in a group of 23 African-American young adults of both genders, yet this association was not corroborated in a much larger cohort of Caucasian young adults (n = 509, also men and women).
Our results need to be corroborated in a study with a larger sample size.
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