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If these cases represent true minicircles, we have been unable to amplify a corresponding sequence to close these circles (note that Figure 3B, vi and vii contain unique sequence relative to vi and viii, respectively).
In most SIP1s the corresponding sequence to the first NPA box is NPT, interestingly this unusual motif is conserved also in PpSIP1s, implying that this is a structurally and functionally important feature of SIP1s.
When we compared this sequence to the related sequence from the AVP1 promoter, a 127 bp region (-631 to -505) in the AVP1 promoter was found as the corresponding sequence to the identified 130 bp region in the TsVP1 promoter.
To produce the hydropathy profile, the hydropathy-scale value [ 18] for each amino acid in a column of the multi-sequence alignment (corresponding to a single position on the profile) was multiplied by a weighting factor that reflects the fractional contribution of the corresponding sequence to the total sequence diversity represented [ 17].
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When the user clicks on the 'Alignment' button, the corresponding sequence-to-structure alignment appears in the drop-down row.
Also we found neither AKT2 nor AKT3 mutation in the corresponding sequences to the AKT1 E17K, indicating that mutational alteration of neither AKT2 nor AKT3 contributes to cancer development.
The C-terminal predicted coiled-coil regions were aligned again for all corresponding sequences to analyze potential oligomerization patterns (see below).
Each sequence of frames related to a certain phoneme at the source is matched to its corresponding sequence at the target, according to the phonetic labeling.
In particular, free energy estimations of predicted structures are employed to ranking corresponding sequences prior to motif search, which, to our knowledge, poses a novelty in this field.
These complex cell-to-cell interactions and corresponding sequence of events leading to degeneration are difficult to capture and recapitulate by ex vivo models of human disease, making development and testing of potential treatments a particularly challenging and expensive endeavor.
These expression signatures may then be matched to their corresponding sequence in the genome to delineate gene expression.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com