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Finally, the quantitation of estrogens after whole blood microsampling was compared with the results obtained with the corresponding plasma samples.
We evaluated a total of 36 frozen packed blood cell samples and 22 corresponding plasma samples from wild Hawaiian honeycreepers.
Metabolomics was applied for the study of PCa bone metastases (n = 20) in comparison with corresponding normal bone (n = 14), and furthermore of malignant (n = 13) and benign (n = 17) prostate tissue and corresponding plasma samples obtained from patients with (n = 15) and without (n = 13) diagnosed metastases and from men with benign prostate disease (n = 30).
In 201 patients with an unknown EGFR mutation status due to technical problems with tumour samples (see above), 12 mutations were identified in the corresponding plasma samples.
Patients DBS samples were extracted and analyzed by the MALDI-QqQ-MS/MS DBS assay, and corresponding plasma samples were prepared and analyzed in duplicate.
Among them, PPP1R3C and EFHD1 were rarely hypermethylated in peripheral blood cells, but frequently hypermethylated in 24 CRC tissue samples and their corresponding plasma samples.
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In comparison, CA181, another patient with limited-stage disease (AJCC stage IIIA), had only three mutations detected in the tumor, all of which were also detected in the corresponding plasma sample.
In this study, we directly compared acylcarnitine concentrations measured in DBS with those in the corresponding plasma sample.
In addition, the total DHA concentration was estimated by summation of HPLC-determined DHA and DHA equivalence of the corresponding plasma sampling times of AS for each individual.
Table 2 summarises the PCDH10 methylation rate of the 63 colorectal tumours and corresponding plasma sample, and their association with various clinicopathological factors.
The recovery was determined for each sampling period as R = (Cout − Cin)/(Cpl − Cin), where Cin, Cout, and Cpl are the measured electrical conductivity in the perfusate, the effluent sample, and the corresponding plasma sample, respectively.
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