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First, we consolidated the results of the 25 items into 12 "diet categories" by combining the items that would be naturally addressed together (e.g., items reflecting meat quality and meat portion size) and averaging the points of the corresponding items for each diet category.
Corresponding items for the genetic score (Web Figure 3, part c) were 2 positive factors (consideration of impact of genotyping errors; information on linkage disequilibrium) and 2 negative factors (no data on allele/genotype prevalence; no assessment of Hardy-Weinberg equilibrium (HWE)).
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In this study, the assessments on the original version of the Functional Barometer (1.0) were compared with assessments on corresponding items of the Balanced Inventory for Spinal Disorders (BIS) [ 35], which is a validated self-report questionnaire that measures to what extent pain affect the physical and mental health, social life and quality-of-life.
To explore potential reasons for this relatively low correlation, we correlated all items of the TBF-12 with the corresponding items of the THI.
A patient satisfaction summary score uses the perceived relevance (importance) of each item (part A) as a weighing factor for the corresponding item from part B. The resulting scale is linearly transformed to result in a range of 0 (completely dissatisfied) to 1 (completely satisfied).
As hypothesized we found that the correlations between the reference labels and corresponding items were high for the clear-case vignettes (0.59 – 0.72) and low for the ambiguous-case vignettes (0.08 – 0.08).
The corresponding items are adjusted for this study.
If one or two items were missing, they were replaced with the sample mean value for corresponding items.
For disclosed data, the visibility of one's favor always depends on the visibility of the corresponding item, whereas for pages, the visibility options are different on the inspected platforms.
For each domain we computed the mean score for the corresponding items, thus the higher the score, the better the quality of life on that specific domain.
The correlation coefficient for the corresponding items in the EORTC QLQ-C30 and the Japanese PRO-CTCAE was high (Pearson r = 0.56 0.76).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com