Oligomers derived from PENA cured at lower temperatures and the corresponding cured polymers show better hydrolytic stability than those of PEPA.
In addition, N-phenylmaleimide (MI) and p-phenyl-phenylcyanate (S-Cy) were utilized as model compounds and mixed via a melting method and a solution method to explore the corresponding cure reactions by means of FTIR, DSC and NMR.
The ratio of phenolic to phenoxy structures (which is representative of the rate of phenoxy-phenolic rearrangement), in each case has been determined by 1H NMR analysis of the corresponding cured mixture.
The clinical cure rate of patients exhibiting <103 CFU/ml on Day 0 was 88.0 % on Day 7 and 98.0 % on Day 37, whereas the corresponding cure rates in patients exhibiting ≥103 CFU/ml on Day 0 were 62.9 % on Day 7 and 77.4 % on Day 37, respectively, and thus significantly lower (p < 0.005).
The corresponding cure proportions were 92% (75%to9898% and 666% (62% to 70%), with an estimated difference in cure of 26%15%to36% 36%).
A total of 18 and 33 thiamphenicol-sensitive colonies, corresponding to curing efficiencies of 50% and 92%, were identified in the three- and seven-transfer approaches, respectively.
Tg values and the thermal stability of polymers arising from the isothermal cure schedules were generally higher than those for the corresponding dynamic cure.
Of 32 patients enrolled for miltefosine treatment 28 patients completed treatment, of which 26 were cured at three months, corresponding to a cure rate of 92.9% on a per protocol analysis, and 81.3% according to intention to treat analysis.
The irradiated PAA film with the hole patterns was then transformed to the corresponding polyimide film with curing at 350 °C for 1 h.
The best mixture and curing temperature, corresponding to activator/zeolite: 0.5, Na2SiO3/NaOH: 3, and 60 °C, was identified by the highest mechanical strength obtained after 28 days of aging of the synthesized specimens, which reached 17 MPa.
