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The decline of a company begins most of the time by mismanagement and unmarketable products (Crutzen and Van Caillie 2009) which may cause a decline in sales over several years (and a correlative decrease in earnings if nothing is done to improve the market position).
In EVTs where endogenous ADAMTS-12 was knocked down using siRNA, av integrin mRNA and protein levels showed a correlative decrease in expression compared to controls (Figure 7A).
A correlative decrease in mRNA and protein levels of MYO1B was observed following miR-363 expression.
Clinical studies suggest a correlative decrease in lifespan and overall decrease in the quality of health in patients that experience chronic levels of pain [ 10].
Likewise, a correlative decrease of the silencing histone modification peak scores was observed at the upregulated genes confirming the net enrichment trends.
The observation that HER2 expression is increased in MUC4-transfected SKOV3 cells is consistent with our previous finding where we observed a correlative decrease in HER2 expression in antisense-RNA-induced stable MUC4-knockdown cells (Singh et al, 2004).
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We demonstrate that reduced Smn levels are correlative with a decrease in transcripts implicated in ribosome, rRNA binding, ubiquitin and oxidative phosphorylation.
Correlative analyses suggest that decreasing pH may impact calcareous species directly, while inducing long-term changes in abundance and of non-calcareous species through indirect effects [36].
In addition, correlative immunofluorescence studies demonstrated decreases in the expression of K+ channel subunit proteins, Kir2.1 and Kir2.3 (Ariano et al., 2005).
Data supporting a role for SirT1 in cell senescence are still correlative; senescent fibroblasts show a decrease in SirT1 expression [ 46] and SirT1 overexpression can inhibit oncogene-induced senescence as a result of direct p53 deacetylation, which counteracts p53 hyperacetylation in oncogene-induced senescence [ 47].
In neurons pre-incubated with Tat-S, NMDA treatment provoked a strong decrease in viability and a correlative increase in death compared with untreated cultures.
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