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In particular, it is demonstrated that the global phase diagram's shape defines the correlative ability of the equations.
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Ideally, such a descriptor should be informative, have good correlative abilities in QSAR applications, and most importantly, be computationally efficient.
CoMFA and CoMSIA models give reliable correlative and predictive abilities but the CoMFA model performance was slightly better than CoMSIA.
The best CoMFA and CoMSIA models had a cross-validated coefficient q2 of 0.733 and 0.738, respectively, which showed high correlative and predictive abilities on both the test set and training set.
Firstly, the structure-Limk1 activity relationship models (3D-QSAR) and structure-Limk1/ROCK2 selectivity relationship models (3D-QSSR) were developed and both 3D-QSAR and 3D-QSSR models showed good correlative and predictive abilities.
"That ability is correlative of brain size in primates.
Moreover, in keeping with the modest increase in GPX4 expression exhibited by the vector control cells, there was also a correlative decrease in the ability of S. Typhimurium to induce PMN transepithelial migration.
This is especially notable with Bcl-XL, and has important implications for clinical correlative studies where the ability to distinguish between different levels of expression of Bcl-XL and other anti-apoptotic proteins by immunohistochemistry is limited, and in which intercellular variability in the expression of Bcl-XL is within this critical range.
Checks and balances at home require a correlative balance of power abroad.
They are, however, correlative and their significance rests on the ability to draw causal inferences about the underlying biology from these relationships.
The ability to make conclusions on the correlative studies becomes underpowered, substantially compromising the risk benefit of performing these procedures.
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