The median slope of the correlation with ground truth equaled 0.55 (Q1 0.43 and Q3 0.77, first and third quartiles) and 0.62 (Q3 0.58, Q3 0.71) for shading and texture, respectively.
Although the programmed ground truth goal state is not directly observable, subjects' responses showed both high validity (correlation with this ground truth) and high reliability (correlation with one another).
Then, we tested which of the internal measures has the highest correlation with the ground truth.
With ischemia data measured from animal experiments, we reconstructed TMPs with roughly 0.9 correlation with the ground truth.
This is done by first extracting a "ground truth" of the clustering quality using external evaluation measures and then checking which of the internal measures has the highest correlation with that ground truth.
However, for our method, the curve is more similar to that calculated by the MEGA method, which again shows that our method achieves the highest correlation with the ground truth.
This consistency suggests that the result from RNA-Skim may have similar correlations with the unobserved truth.
Success would offer new insights into the development of breast cancer precursor lesions, allow testing of the important 'sick lobe' hypothesis, improve correlation with imaging studies and provide 'ground truth' for mathematical modelling of breast growth.
To a deflationist, the meaningfulness of truth-bearers has nothing to do with truth.
This preoccupation with truth is based on the implicit assumption that truth has some overriding value.
