Apart from the observation of amino acid positions at all transmembrane helices with correlations to effects on several G-protein subtypes (Gi, Gq, and Gs), we also revealed residues selective for either Gs, Gq or Gi (figures 5-6).
Linking the effect of immigration on the correlation to its effect on the joint probability of work and childbearing, an innovation of this study, would not be possible without the grouped model.
These factorial correspondence analyses clearly show strong positive correlation between the effects of ACC and PCIB, and their negative correlation to the effects of IAA treatment, whatever the regulatory level measured: transcript accumulation or carotenoid accumulation.
This interface is defined here as the type of concentration that gives the best correlation to ecotoxicological effects and is called the ecotoxicologically relevant concentration (ERC).
When we applied partial correlation to remove the effect of foreknowledge (i.e., proportion of respondents who marked the particular species as known), the relationship between mean scores and zoo population size remained significant (r2 = 13.7%, p = 0.021).
In original GSA, the gene-level measure is typically a fold-change or a correlation to represent the effect of a single gene.
For example, there is some evidence that increased expression of the human SEL-1 ortholog, SEL1L, correlates with a decrease in tumor aggressiveness (reviewed in [4]), but how this correlation relates to effects on Notch activity is not clear.
We investigated the in vivo efficacy of a Shh antagonist, cyclopamine, in correlation to the secondary effects induced by this treatment on gastrin levels and acid secretion.
In this regard we would like to highlight positions with a high number of descriptors and a strong correlation to antagonistic signaling effects on the one hand: 2.64, 4.60, 5.36, 5.40, 6.58, 6.59, 7.33, 7.39, and a specific correlation to agonistic signaling effects on the other hand: 1.31, 1.36, 2.60, 2.63, 3.33, Lp2.49, Lp2.51, 7.32.
We performed partial correlation to separate the effects of L1 gene fractions and GC content on both PE and BE.
