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The meta-analysis algorithm aggregated scores for various ontology terms associated with the correlated signatures, weighted by the strength of the correlation score (Figure 4, Methods).
(i) Best Correlation Score (min).
Nonetheless, it tends to improve the correlation score.
Consistently, the Perceptual Spectral Centroid gives the best correlation score (see Appendix D).
A correlation score is used in order to filter some of false detections.
Motivated by previous studies [4, 8], we also tried to maximize the correlation score by selecting a subset of genes.
This test resulted in a correlation score of 0.1981 with a p value of less than 0.001.
The approach adopted draws on tools in the areas of data mining and pattern recognition including the techniques of Fisher correlation score and self-organising maps.
SEP54 was detected only once with high X correlation score in Sample 15 and was encoded from a sORF in lncRNA Gm2670 (Table 2, Fig. 4D).
The neighborhood of a grid point is scanned more thoroughly only if the grid point produced a high face correlation score.
A threshold is used to reject the unstable candidate matches with a low correlation score, which is set to be 0.75 in our experiments.
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