Sentence examples similar to correlation of functional polymorphism from inspiring English sources

To assess the correlation between the density of functional polymorphisms (missense and nonsense mutations) and intronic burden, we used the dbSNP database.

These polymorphisms, including MTHFR C677T in our research, were all striking examples of functional polymorphisms being strongly selected for in human population in response to environmental stresses.

MiRNA-polymorphisms (miR-polymorphisms or miRSNPs) are a novel class of functional polymorphisms present in the human genome [33], [34].

In the second, we apply Principal Component Spectral Analysis to separate correlations due to functional polymorphisms from those due to population structure.

Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders.

We did not see differences in hormone responses resulting from expression of this functional polymorphism.

Some of the reported associations, mostly in populations of European descent, have already set the bar high in the field with 'high-quality' studies, either with well-powered studies [ 36, 41] or with a functional correlation of the associated polymorphism [ 43].

Moreover, we found an association of this CD45 functional polymorphism in thymuses with the CCR5 Delta 32 mutation (p = 0.00258).

The correlations could be due to functional polymorphisms or to population structure.

This is quite possible, because our correlation analysis also pointed to the presence of other functional polymorphisms.

A functional polymorphism of COMT, Val108/158 Met, affects prefrontal function, and the high-activity Val allele has been reported to be a genetic risk factor for schizophrenia.