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One-way ANOVA, Pearson product moment correlation, and Spearman rank correlation coefficient analyses were performed in SPSS ver.16.0 to examine the variation and relationship of variables.
For correlation coefficient analyses (Figure 6D), cross-correlation histograms were first normalized and z-scored.
We thank Kun Xie for providing technical support and Dr. Meng Li for suggestions on the correlation coefficient analyses.
Our correlation coefficient analyses (see Materials and Methods) revealed that there was significant difference between recorded spikes and shuffled spikes for both DA and non-DA neurons (P<0.001; Figure 6D), thus suggesting that both putative DA and non-DA neurons exhibited significant rhythmic activity during voluntary wheel running.
With the exception of the Cox proportional-hazards regression and intraclass correlation coefficient analyses, which were conducted using SPSS software (SPSS Inc., Chicago, IL, USA), all statistical calculations were undertaken using the statistical package built into the GraphPad Prism 5 computer programme for the Macintosh (GraphPad Software Inc., San Diego, CA, USA).
Correlation coefficient analyses indicate the expression of E2F2 (TTHERM_00695710) and Dp-2 (TTHERM_00047010) and of E2F3 (TTHERM_01099150) and Dp-2 (TTHERM_00016400) are highly correlated (Table 11), suggesting they may reside in distinct complexes that are involved in the regulation of transcription during early and late conjugation, respectively.
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The intraclass correlation coefficient analysing interobserver variability of GLPS was 0.92 (P <0.001).> -wrap-foot> Dare are presented as median (IQR) or number, as appropriate.
The results from the partial correlation coefficients analyses were consistent with these associations (Table 5).
Analysis of the raw phenotype data, including Pearson's correlation coefficients, analyses of variance, and Student's t-test (for comparing NILs to parental inbreds) were conducted in R (The R Project for Statistical Computing).
The analysis of prognostic factors was performed using the Cox proportional hazard model by Prism 5, and Spearman's rank correlation coefficient was analysed by Prism 5. Differences were considered to be statistically significant if the P-value was <0.05.
Kappa statistics and intraclass correlation coefficients (ICC) analyses were used to examine the inter-rater reliability.
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