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Omberg et al. use higher-order singular value decomposition on DNA microarray data, obtaining the core tensor of eigenarrays × x-eigengenes × y-eigengenes and finding correlation between genomes in the subtensors of the core tensor [ 16].
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This is consistent with previous observations indicating a positive correlation between genome size, TE content and genomic methylation levels36.
Comparative genomics studies the correlation between genome structures and functions across different biological species.
For genomic shotgun sequencing projects, there is a correlation between genome coverage and the percentage of natural duplicates.
By contrast, a negative correlation between genome size and the density of SSR loci was revealed.
In this paper, a correlation between genome-wide MBD binding and mCpG density is shown.
There is a striking correlation between genome size and the direction of silencing in interspecific hybrids.
First, we do not see any close correlation between genome type and geographical location or time of isolation.
Previously Lynch and Conery [6] showed strong positive correlation between genome size and gene number in multiple species.
The lack of correlation between genome size and organismal complexity is understood in terms of the massive presence of repetitive and non-coding DNA.
Methodologically, the EWAS takes inspiration from GWAS, which have been used to assess the correlation between genome-wide variability and disease.
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