In particular, we examined the response of the patients in this group who lacked all three putative predictors of anthracycline responsiveness and also correlated response with HR status.
MacLean and Bell [30] observed more divergence for correlated traits when they assessed the growth of Pseudomonas fluorescens populations evolved in an environment with one limiting resource, and subsequently tested the correlated response in almost 100 alternate environments.
Our analyses focused on predicting the correlated response of larval size after a single generation of selection on adults.
The authors correlated response with pretreatment levels of microRNA29b (miR29b), an miRNA that specifically inhibits DNA methyltransferase expression.
Interest in tamoxifen metabolites started with a report by Goetz and colleagues [ 60] which correlated response to tamoxifen with CYP2D6 polymorphisms.
Therefore, correlated response to selection for narrow window of emergence would provide evidence for mechanisms that influence both timing of emergence as well as life history traits.
It may eventuate that some NKTs are favourably correlated with some of the KTs, and in this situation the correlated response of the NKT to selection on the KTs means that the NKT may also benefit indirectly.
Body mass is not itself the target of selection but is genetically correlated with traits under strong positive directional selection, leading to a correlated response to selection.
Simultaneous optimization of the correlated response variables has become more important in complex systems.
Prediction of correlated response is important in breeding program design and in interpreting the consequences of natural selection.
In the context of quality engineering, these problems usually include correlated response variables as well as correlated covariates.
