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We wanted to determine whether correlated domain pairs might represent protein complex cores.
We wanted to determine whether proteins containing these correlated domain pairs tended to interact directly.
Having determined that both species have protein complexes with correlated domain pairs, we wanted to determine the role of these pairs in the complexes.
This suggests that both interacting proteins with homologous domains and entirely non-homologous proteins with correlated domain pairs are involved in evolutionary cores of yeast protein complexes.
Neither proteins with homologous domains nor correlated domain pairs were significantly older than other proteins in the Arifuzzaman [ 25] and Butland [ 24] Exp-TAP E. coli datasets.
As expected, more closely related species tend to have more highly correlated domain family sizes and there are clearly two distinct clusters, one for green algae and the other for land plants.
Similar(49)
The experimental results suggest that the phrase-based CRF model benefits from the flexibility to use correlated domain-specific features that describe the dependencies between TFs and other entities.
The formation of correlated domains reported to hydrogenated graphene is no longer observed in graphdiyne cases.
Intelligent e-Learning tools, able to optimally complement or replace traditional instruction in certain specific and correlated domains are currently being developed.
This would account for a failure to identify correlated domains as E. coli complex cores.
Although the Krogan dataset supports the finding that correlated domains are older than other proteins, the test for homologous pairs was not quite significant.
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