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As no protective neutralizing correlate is established, GMT and SCR (defined as ≥4-fold increase in titer relative to the baseline value) were used to characterize the immune response.
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The relationship of this dichotomous variable to other clinicopathological correlates was established with the Chi Square test or the Fisher's Exact Test, as appropriate.
This genotype phenotype correlation was established by correlating the rate of α1-antitrypsin polymerization in vitro with the clinical manifestations caused by each mutant of α1-antitrypsin (8).
As no correlate of protection is established for B. pertussis, a vaccine response to this vaccine component was defined.
Firstly, an optimization model of machine settings modification considering the residual ease-off is established by correlating the tooth flank represented by universal machine settings.
For instance, where the correlate has been established for a vaccine that has already demonstrated clinical efficacy against disease, the correlate simplifies study of the vaccine in new populations, age- or risk-groups by permitting clinical trials to be conducted with immunogenicity endpoints and avoiding large-scale efficacy trials.
As no immune correlate has been established for this malaria vaccine, we sought to characterize the humoral and the cellular immune response.
No socioeconomic correlates could be established for Cocaine hotspots.
Once the correlating variables were established, forward stepwise multiple linear regression analysis was performed to relate REE (kJ/min) to FFM (kg), FM (kg) and age in all subjects and to relate LM to FM and height for female subjects and LM to height and BMC in male subjects.
Also, in this respect, further improvement of the implementation of clinical data and genotype phenotype correlates will be established by the implementation of phenotypic ontology [Köhler et al., 2012], allowing to associate genetic variations with specific clinical characteristics rather than disease diagnoses.
One of the suggestions with the aim of overcoming this and related limitations is a potential use of the other scale A B Neuropsychological Assessment Schedule (ABNAS), which seems to be more explicit; however toxicity level correlate has not been established [35].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com