Sentence examples for correctly transported from inspiring English sources
To this end, it is noteworthy that a PEXEL containing RESA-GFP chimera was only correctly transported to its correct sub-cellular location when expressed under control of its endogenous promoter.
This study revealed four distinct loss-of-function mechanisms for the mutant hNav1.5 channels (Fig. 7): First, mutants R878C and G1408R were correctly transported to the plasma membrane, but did not form functional channels, suggesting a complete gating/permeation defect.
The deletion mutant T1223del was correctly transported to the cis-Golgi apparatus and showed co-localization with GM130 (Fig. 4).
The mutants T644M and T1223del that were correctly transported and proteolytically cleaved into mature α- and β-subunits exhibited 50 and 85% of GlcNAc-1-phosphotransferase activity, respectively, of the WT enzyme.
The work presented here raises the possibility that such effects are related to CALM's ability to directly drive the endocytosis of the small R-SNAREs VAMP8, VAMP3, and VAMP2, since failure to correctly transport these small R-SNARE VAMPs to early endosomes as a result of a reduction in CALM levels would perturb subsequent trafficking of a wide variety of proteins through the endocytic pathway.
When you perform them correctly, audiences are transported back to when they first heard them.
Since outer segments with membrane discs can only develop if opsin is transported correctly we assumed that there was no trafficking defect in these cases.
The main reasons for failure of bacterial growth in culture, from correctly collected and transported specimens, stem from bacterial and fungal contamination and the lack of fresh media [ 24].
Cells were initially plated at a density of 1×105 cells/cm2 for 4 days; at this point functioning bile canaliculi were formed, confirmed using the ABCC2-specific substrate carboxydichlorofluroscein, which will only be transported in correctly polarised cells [26] (data not shown).
Subsequently, correctly folded proteins are transported to the Golgi apparatus.
The correctly folded proteins are transported to the Golgi compartment where further modification of the proteins takes place and the proteins are thereafter secreted out of the cell.
