Sentence examples for correctly traffic from inspiring English sources
In such a scenario, the pleiotropic, multi-functional nature of the exocyst would be due to its usage by the organism to correctly traffic different sets of developmentally-appropriate vesicle cargoes.
Do they know that the alanine variant is made and correctly trafficked to the plasma membrane?
Our results also showed for the first time that virally expressed exogenous protein was correctly trafficked intracellularly to its native membrane location (Fig 2).
Unlike the rex1 knockout or Hsp101 protein knockdown (Beck et al., 2014), PfEMP1 appears to be correctly trafficked in FCR3Pf vap1Δ knockout parasites.
Our experimental data, based on immunofluorescence of connexin proteins in HeLa DH cell transfectants (Fig. 2), strongly suggest that the mutated protein is correctly trafficked to the plasma membrane but fails to form gap-junction plaques, confirming that the extracellular cysteine pattern is fundamental for the docking of opposing hemichannels.
CaBP1-Long, CaBP1-Short and CaBP2 all harbour an N-terminal myristoylation consensus sequence and our results show that these isoforms were correctly trafficked and efficiently membrane associated, localising to both a peri-nuclear region resembling the Golgi apparatus and the plasma membrane (Fig. 1B D).
Depending on the extent of ER processing, some fraction of the protein can be correctly processed, trafficked to the lysosome and retain functionality, even in individuals carrying disease-associated mutations.
This suggests that, in SEC23A-deficient hair cells, USH proteins are trafficked correctly and that the trafficking phenotype we have observed is specific to USH mutants.
But intercepting and correctly analysing that traffic is at the heart of the global counterterrorism response.
(a) The ΔF508 variant of CFTR is characterized by ER accumulation, misfolding and an inability to traffic correctly to the plasma membrane where it functions as a chloride channel.
To correctly estimate the traffic amount or the number of active nodes, the capture effect should be excluded.
