Sentence examples for correctly repaired from inspiring English sources

If genomic instability resulting from this DNA damage is not correctly repaired, it leads to mutation, cancer and cell death.

He suspects the experiment worked because it took advantage of an apparently rare phenomenon called gene conversion in which DNA sites already inactivated by CRISPR helped stop other recently cut sites from being correctly repaired by the cell, leading to a snowball effect that resulted in all the PERV copies ending up deactivated for good.

DNA damages can be recognized by enzymes, and, thus, they can be correctly repaired if redundant information, such as the undamaged sequence in the complementary DNA strand or in a homologous chromosome, is available for copying.

DNA damage blocks transcription and replication, and if not correctly repaired, could introduce detrimental mutations or cause cell death.

These breaks can lead to genomic instability resulting in translocations, deletions, duplications or mutations when not correctly repaired [ 9].

In summary, the slipped-junction conformation can determine whether expansion intermediates will be correctly repaired (excising the excess repeats), escape repair (retain the excess repeats as a heteroduplex), or be processed to expansions (incorporating the excess repeats).

Also, because of the many genetic changes that occur in tumors they are generally less able to repair or correctly repair radiation-induced DNA damage.

Central to this process is the ability of cells to accurately recognize and correctly repair DNA damage in a timely manner to then allow regulated and orderly progression through the cell cycle.

Consistent with the need to correctly repair recombination events mice deficient in MSH5 or MLH1 exhibit disrupted spermatogenesis and are infertile [59], [63].

Thus, this selective loss may be caused by the failure to correctly repair the locus after recombination.

In other cases the site where a class II element is cut out of the genome is not repaired correctly, resulting in mutations that interfere with gene regulation and thereby cause cell dysfunction.