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Sequential Bonferroni corrections for k multiple tests were applied where appropriate [35].
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Norm-conserving pseudopotentials (with nonlinear core correction for K) and an energy cutoff at 60 Ry were used.
However, we detected highly significant linkage disequilibrium for 3 nuclear locus-pairs across populations after a sequential Bonferroni correction for k tests (k = 703, p < 7.1 × 10-5): One_MHC2-190 (I = 0.433) and One_MHC2-251 (I = 0.465); One_Tf_ex10-7 (I = 0.632) and One_Tf_ex3-18 (I = 0.084); One_GPDH (I = 0.668) and One_GPDH2 (I = 0.082).
An excellent agreement between the present results and experimental data [48, 51] has been achieved due to the Hartree [39] local-field correction function for K, Pb, and Bi.
A naïve Bonferroni correction for 14 k variants would give a P value threshold significance of 3.5 × 10−6 (=0.05/14000) when controlling the family wise error rate (FWER) at the 5%% level.
k corrections for the SNPs on the Affymetrix 10 K microarray were available from a panel of 33 Caucasian individuals assayed on separate microarrays and applied to each SNP (see Methods).
In this process, we use background random corrections to reduce noise only for K > =4.
We surmise, therefore, that V r in tumors (and healthy tissue) will never deviate too much from the value of 0.53, ml/ml used for K s correction in this study.
Nevertheless, since 1/S' lacks correction for superimposition when K increases above 1.5, 1/S' can overestimate K when comparing closely related baculovirus genomes.
In order to characterize the star we present a new set of empirical relations between the density, radius, mass, bolometric magnitude, and V-, J-, H- and K-band bolometric corrections for main sequence stars with M < 0.80 M, or spectral types later than K5.
Without correction with k for unequal representation of alleles (see Methods) the allele frequencies we estimated from the pooled analyses correlated well with the true frequencies derived for each sample from the HapMap (r = 0.959 for the parents and 0.961 for the offspring).
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