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The similarity correction step corrects the relative observed abundance ri of proteome P i by estimating the true abundance ci.
We therefore added a sequence correction step to our processing pipeline [25], correcting common 454 indel error-patterns to match the transmitted virus.
In all cases a further correction step is required after normalisation to correct for the batch effect.
To correct for multiple comparisons, we included a false discovery rate correction step [ 14].
These estimates are then improved in the correction step.
The fifth-order accuracy of the spatial derivatives is ensured by a flux correction step.
The correction step consists in coming back on the curve using a Newton-like method.
Therefore, future work should aim for compensating SBR dependencies in the correction step.
The correction step is the same as in the classical Kalman filter.
But their methods [22, 23] do not have overrelaxation or correction step.
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