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Acquisition, attenuation correction, reconstruction and analyses of SPECT data were performed as previously described [ 1].
With further use of 3D motion correction, reconstruction and quantitative image analysis techniques like those used in this study, we are hopeful that our knowledge of early structural changes in the human fetal brain in utero can continue to be improved and expanded upon.
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Tremendous fundamental advances in time, energy, and spatial resolutions; sensitivity; data corrections; reconstruction; and information extraction still remain to be realized [1, 4].
Images were reconstructed using OSEM3D algorithm with CT attenuation correction (hybrid reconstruction, 4 iterations, 10 subsets).
T16 system, with low energy parallel hole collimators and underwent standard CT-based attenuation correction during reconstruction.
Addition of the Gaussian filter and point spread function correction during reconstruction further improved visual and quantitative precision.
The mechanical features of and biologic response to using distraction osteogenesis with the circular external fixator are the unique aspects of Ilizarov's contribution that allows deformity correction and reconstruction of bone defects.
The next step must therefore be its validation within a complete PET attenuation correction and reconstruction pipeline, in order to determine whether the differences reported here with respect to previously published approaches do indeed lead to a significant improvement in the resulting emission images.
Attenuation correction and reconstruction processing was done according to FDG PET.
Thirdly, online (continuous) motion correction during reconstruction is not trivial and some difficulties with normalisation and attenuation correction still need to be investigated further [ 7].
In the era of PET/CT, the better differentiation of physiological FDG uptake from pathological accumulations, the improved attenuation-correction and reconstruction algorithms, and the more precise localisation of abnormalities, are likely to more accurately define appropriate further investigation strategies, or to allow definitive treatment selection.
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