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Correction for clustering effects was not needed as the intraclass correlations between school and MVPA were below the conventional value of 0.05 (ICC = 0.04).
This approach yields an estimate of 302,000 cases in Mexicans; additional correction for clustering in Spanish cases, if the required data were available, would further reduce this figure.
We made no additional correction for clustering.
The seventh column shows the results of the pooled OLS with a correction for clustering.
Adjusted for gestational age, gender, and birth year using robust standard error correction for clustering.
First, the multivariable regression was performed using pooled Ordinary Least Squares (OLS) regression, including a correction for clustering.
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Adding 10% for possible loss to follow-up, and 38% correction factor for clustering effect on village level [ICC = 0.01], the total sample size came to 583 (approximated to 600).
After multilevel corrections for clustered data and possible differences in patient mix between the years, the decrease in preventable AE rate in 2011/2012 was still clearly visible with a 'decrease' of 30% in comparison to 2008.
However, it should be noted that in the PD group, at a low threshold of 0.001 uncorrected for multiple comparisons, and no correction for cluster size, a symmetrical cluster of age-related atrophy was observed in the middle corpus callosum.
In doing so, we made a correction for clusters of the variance covariance matrix to obtain a robust estimate in the second stage.
The apparent 10.2/7.6 mmHg difference between inpatients and outpatients was only slightly reduced to 8.0/5.1 mmHg after adjustment for baseline and remained highly significant (p < 0.0001/p < 0.0001) even after correction for cluster effects.
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