In total, this study performed 18 GWAS, increasing the multiple testing burden; correction for multiple testing was limited to the single GWAS.
For association tests, the module eigengenes are included in the regression models from Additional file 2: Table S2, similar to the expression probes, and adjustment for multiple testing was performed using Bonferroni correction, where the burden is reduced in comparison with a probe-based analysis.
The teacher takes on some responsibility for correcting but places the burden of correction on the learner and leaves it up to the individual student to make the actual correction.
Several population‒based surveys have reported URE or presenting corrected (with habitual correction) VA point out the enormous burden of URE as reversible and amenable to rehabilitation VI cause [ 4, 5].
This study aims to evaluate the association between the functional independence of children after postnatal spinal dysraphism correction and informal caregivers' burden.
Like many senior officials, he knew very well that a crisis over Britain's budget contribution was unavoidable and that a substantial correction to the inequitable burden was essential, as indeed the founder members of the EEC had promised when Britain joined.
Tyre is suffering malnutrition and obesity simultaneously.In this section Out of the comfort zone Into the meat-grinder Feast and famine Barrel of laughs The iron lady Move over, brother Correction: Somalia ReprintsThis "dual burden" is growing everywhere, but nowhere as quickly as in the Arab world.
Hubbard: We've had decades of merger mania, and I think it makes sense to make a significant course correction by putting the burden on the merging parties.
Assuming independence of genes, a genome-wide Bonferroni correction for gene-based burden tests in WES studies is 0.05/20,000 = 2.5 × 10−6.
For each feature tested (genes, intergenic, and pathways), the majority of bins had statistically significant differences (adjusted using Bonferroni multiple testing correction) in rare variant burden.
