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In sharp contrast, adding rhTSP-1 to platelet releasates from Thbs1−/− mice fully corrected the defect in stirring-induced activatibility (Fig. 2F).
As shown in Figure 4B, there was no evidence that attachment of the YTRF motif corrected the defect in receptor degradation in cells expressing the Δ716 G-CSFR.
Expression of the wild-type IMP3 allele in the IMPQ strain (complemented IMPQ strain) corrected the defect in 40S subunit production, restoring a wild-type ribosomal subunit ratio (60S/40S ratio of 2.7, Figure S1).
Most importantly, the addition of rhTSP-1 to the Thbs1−/−mice samples fully corrected the defect in TGF-β1 activatability, providing strong support for the interpretation that the differences we observed with sera and platelet releasates are unlikely to be due to differences in proteins other than TSP-1.
Normalisation of fasting plasma glucose with weight loss corrected the defect in insulin receptor tyrosine kinase [ 102], indicating that the defect is acquired.
The feedback loop from the actual experience does not change the basic assumptions or decision-making rules that govern the action that corrected the defect.
Similar(52)
Since PLCβ cleaves PIP2, this observation suggests that the accumulation of PIP2 corrected the defects.
Elevating free carnitine levels in insulin depleted diabetic animals with a fixed and relatively inadequate availability of glucose as a myocardial fuel apparently corrected the defects in myocardial function by providing more intracellular fatty acids as an energy substrate.
In other forms of NIDDM, both the acute insulin release and TDP are impaired [ 20- 22] and the correction of the defect in the TDP pathway may automatically correct the defect in direct insulin release.
By Aug. 7, 1978, steel plates to correct the defect had been designed.
Better yet, some say, will be the application of techniques already technically feasible to correct the defect genetically even before a child is born, or soon enough afterward to prevent tissue damage.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com