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After correction for work-up bias, the corrected sensitivity and specificity were 82 +/- 6% and 59 +/- 2%, respectively.
Assuming that the sensitivity and specificity of HRA directed anal biopsy for true HSIL is the same as reported by Byrom (74% and 91%, respectively) and also assuming the conditional independence of HRA cytology and HRA biopsy given true disease status, we found the corrected sensitivity and specificity of HRA cytology to be 89% and 96%, respectively (Table 2).
Using these methods on our example data set, gives a corrected sensitivity of 57% (67/117) and specificity is 91% (350/383).
From the presented tables and figures for men aged < 60 years, we observe that the corrected sensitivity remained at 100% for PSA < 0.9 ng/ml.
The accuracy of a model is defined as the average of its so-called "corrected sensitivity" and "corrected specificity", where the corrected sensitivity of a model is the usual sensitivity plus half of the proportion of unclassified stroke patients, and the corrected specificity of a model is the usual specificity plus half of the proportion of unclassified controls.
For example, we estimate that changing the number of false negatives to 25 would result in a corrected sensitivity of 68%, and to 40 would result in a corrected sensitivity of 62%; these estimates are not importantly different from the reported sensitivity of 65%, and are nearly within the reported 95% confidence interval.
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We also evaluated a high-dose saturation up to 20 kGy, corrected for sensitivity changes.
The apparent prevalence (AP = pos/n, where 'pos' is a random variable representing the number of positive animals in a sample of size n from the wild boar population) was calculated and corrected for sensitivity (Se) and specificity (Sp) using the Rogan-Gladen estimator, yielding the true prevalence (TP = (AP+Sp−1)/J, with J = Se+Sp−1) [10].
Given the impact of geographic region on the diagnostic accuracy of rK39 ICT, we corrected the sensitivity analyses for region effects and limited the analyses to 15 studies performed in the Indian subcontinent and East Africa.
To do so, we searched PubMed, on 6 January 2015, using a search algorithm for the year of publication 9 and a search filter for clinical trial research (clinical trial [pt]) (corrected for sensitivity and precision).
With tubes having the correct sensitivity, it is possible to quantify H2S production in small fermentation lots (0.5-20L 0.5-20Lquantify elemental sulfur levels in wine.
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CEO of Professional Science Editing for Scientists @ prosciediting.com