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Since the total free binding energy of a 3'UTR was compared with its dinucleotide shuffled counterparts, the results obtained did not need to be normalized or corrected for length or G+C content effects.
When we repeated adjusted analyses using only the women's first pregnancies, regression coefficients were of similar magnitude as those presented in Table 2. Estimates of the associations of life stress and emotional symptoms during pregnancy, with placenta weight at birth not corrected for length of gestation, are provided online (see Table S2).
Cox regression analysis: outcome revision aseptic stem corrected for length and gender showed no significant difference, p = 0.22; outcome revision aseptic cup corrected for length and gender showed no significant difference, p = 0.07.
The predicted heart rate was corrected for length, age and sex, making use of a standardized table [ 24].
Having corrected for length of follow-up, no statistically significant difference in the frequency of features analysed was observed.
Area under the receiver operating characteristic (ROC) curve (AUC) values of the gene set-motif combination pairs were corrected for length bias.
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The package corrects for length bias present in RNASeq data.
To correct for length differences between datasets from different tissues, we selected 750 bp in the middle of the reported enhancer sequences.
Over-represented Gene Ontology (GO) terms and KEGG pathways among the DE genes were detected using the software GoSeq [ 49], because GoSeq corrects for length bias in RNA-Seq data.
In all statistical analyses (see below) the intestine length was corrected for standard length using ratio of intestine length and standard length and intestine weight was corrected for total weight using the ratio of intestine weight and total weight.
No significant effect of fish group on intestine length corrected for body length was found (p > 0.05), but a significant effect of season on the same parameter was determined (p < 0.001), with a higher value in autumn compared to other seasons (p < 0.001) and a higher value in summer compared to spring (p < 0.001).
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