Sentence examples for correct replication from inspiring English sources

Inactivation of the ubiquitous DNA mismatch repair pathway, whose normal function is to correct replication errors and hence increase replication fidelity, is often the cause of the mutator phenotype.

Second, another polymerase might proofread and correct replication errors made by Pol IV.

MMR is a replication-coupled repair function that acts to correct replication errors, thereby limiting the frequency of spontaneous mutations.

Loss-of-function mutations in either mutS, mutL, or uvrD abolish MMR, leading to significantly elevated spontaneous mutation frequencies, due in large part to an inability to correct replication errors [35].

This approximation is valid if the probability of correct replication per base (denoted by q) is sufficiently large so that d is small.

The correct replication of telomeres and, thus, the bypass of the "end replication problem", is performed by the specialized enzyme telomerase (Collins 2008).

Here, we perform a fully "corrected" replication of R&C's model with both bugs removed.

In Experiment 4 (Section 'Experiment 4: corrected replication of R&C's brokerage model'), we present a "corrected" version of R&C's results, without the reservations and payment bugs.

The effects of the reservations bug (Section 'Experiment 2: the reservations bug') and payment bug (Section 'Experiment 3: the payment bug') identified in R&C's implementation are then demonstrated, before a set of "corrected" results for R&C's model are presented (Section 'Experiment 4: corrected replication of R&C's brokerage model').

DNA mismatch repair (MMR) has been extensively characterized in diverse bacteria and eukaryotes and has been shown to play several critical roles in safeguarding genomic information including correcting replication errors and regulating recombination rates and patterns [106], [107].

MMR proteins form a complex that detects and corrects replication errors.