Your English writing platform
Discover LudwigExact(2)
This is a very poor outcome for patients, and will cost the government more in the longer term as the diagnosis of disease is deferred as is the opportunity for prevention of disease, meaning patients will become sicker without the positive interventions provided by the correct pathology diagnosis.
These mice have proved useful in showing that both bone marrow transplantation and gene therapy can eliminate Gaucher cells (Enquist et al., 2006), and that only a modest increase in GlcCerase activity is required to correct pathology (Enquist et al., 2009).
Similar(58)
Conversely, there is a need to develop novel dietary interventions to correct pathologies associated with ether lipid deficiency.
In addition, co-injection of a control FKRP mRNA or mutated FKRP mRNAs either corrected pathology or mimicked human clinical conditions.
Use of this analysis on a larger population can quantify the effectiveness of the tibial resection for correcting pathologies, potentially reduce imprecisions in the surgical technique, and enable development of instrumentation that reduces the risk of resection recuts.
Administration of a CAMKIV inhibitor to these mice was able to prevent and even correct disease pathology [ 50].
In MPSIIIB mice, intravenous administration of AAV9 was able to correct the pathology in the CNS and the periphery.
In all of these, delivery of enzymes across the BBB to correct CNS pathology and prevent the devastating cognitive impairment is the major unmet need.
As the reversibility of renal function may be dependent on the pathogenesis of renal disease, correct renal pathology is necessary for successful treatment.
Previously, it was postulated that the failure of current treatments such as cyclodextrin (CYCLO) to correct the pathology of tissues such as the lung was due to the inability of CYCLO to reach lung macrophages (27, 34).
Our results demonstrate that myotubularin replacement in a mouse model of the disease is sufficient to correct the pathology and strength of affected muscles and thus opens novel perspectives for therapy in patients with myotubular myopathy.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com