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In summary, we here provide solid evidence that polyamines (i) are associated with mast cell secretory granules, (ii) are important for the correct maintenance of granule homeostasis (including appropriate storage of histamine) and our results (iii) suggest an important role for polyamines in regulating the complex machinery that leads to the formation of these organelles.
The binding of PARP-1 to DNA strand breaks and its subsequent catalytic activation might limit SIRT1 activity and, therefore, impede the correct maintenance of mitochondrial homeostasis.
Epigenetic isolation is necessary for correct maintenance of genomic imprints as imprinted domains are often interspersed among nonimprinted domains [ 5, 6], necessitating their isolation from flanking regulatory regions.
53 Regulation of IOP depends on the balance of complex mechanisms involved in the production and outflow of aqueous humor, including the stability and survival of cellular phenotypes involved in this process and the correct maintenance of homeostasis.
In the case of Mbd1, the associated activity was attributed to the Setdb1 methyltransferase and this interaction was proposed to play an essential role in the correct maintenance of H3K9 methylation in heterochromatin during DNA replication.
The impact of lameness may by very costly [ 11], but it can be reduced by treatment of affected piglets and by a correct maintenance of the floor surfaces [ 12].
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Consequently, correct maintenance and expression of mtDNA is essential for cell viability.
One of the key requirements for correct maintenance testing is the reason for the test.
Therefore, LMα1LG4-5 has a crucial role not only for myelination of the spinal roots, but also for correct myelination, maintenance of myelin, proper axon-Schwann cell interaction and peripheral nerve homeostasis in the distal peripheral nervous system.
Correct usage and maintenance of a balance is a basic skill that is essential in any laboratory procedure.
This tight coupling between bone resorption and bone formation is essential for the correct function and maintenance of the skeletal system, repairing microscopic skeletal damage, and replacing aged bone.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com