We utilized this feature under both the default and non-default settings of the CRISP program to arrive at qualitatively correct results in both cases, see Tables 3, 4, 5 and 6.
In the blinded retrospective analysis of two children with diagnoses that had previously been established by conventional diagnostics, rapid pulsed WGS followed by our pipeline consisting of MIP, dbCMMS, Chanjo and Scout, resulted in presentation of the correct pathogenic variants in both cases.
Using the Negex test set, both FMA and MetaMap extracted and assigned a negation status for terms from 1035 test sentences, of which both algorithms were correct in 979 cases, both were wrong in 12 cases, FMA was wrong and MetaMap right in 28 cases and MetaMap was wrong and FMA right in 16 cases.
Table 5 contains a list of the miRNAs, while Table 6 contains a list of the methylated genes (multiple test corrected p < 10-16 in both cases, see Methods).
Finally, two numerical examples are presented: a test problem and a real-data scenario, we corroborate the correct behavior of the method in both cases.
In both cases, correct folding of proteins is managed by chaperones such as those of the GroEL family.
In both cases, correct targeting was confirmed by intracellular dye filling and reconstruction of dendritic arborizations at the end of the recordings.
In both cases correcting for patient characteristics did not change the pattern either.
Limiting this analysis to the 148 malignant lymph nodes that were visualised on PET/CT, the small-voxel score was correct in 132 cases (89%) while the standard-voxel score was correct in 113 cases (76%), p < 0.001.
The occurrence from time to time of investor protection failures in these funds, however, raises the awkward question of whether this assumption is correct in all cases.
